Research Interest: Histopathology, Anatomical pathology, Experimental oncology

Research Interest: To Study How Our Immune Systems Recognize “Self” (The Host) Or “Non-¬‐Self” (Foreign Material) Antigens, And How The Break Of These Processes Leads To The Consequent Disease Pathology, Including Infectious Diseases And Autoimmune Diseases.

Dr Vijai K Agnihotri received his Ph.D. from CSIR-Indian Institute of Integrative Medicine, Jammu, India/Kanpur University. During Ph.D. he screened saffron, Achillea millefolium, Bunium persicum, Mentha pulegium, Angelica glauca for their chemical and biological profiling. After Ph.D., he moved to National Center for Natural Products Research, University of Mississippi, USA for postdoctoral studies. During PDF he had isolated a number of novel molecules and assessed their biological activities. During PDF, screening of Nymphaea caerulea flowers, a marijuana substitute was found having a very good antioxidant activity and can be used for the treatment of oxidative stress related diseases. He then moved back to India and joined CCRAS (AYUSH) as a consultant. At CCRAS he contributed in TLC atlas of API Part-I Vol-I and API Part-I Vol-V. At present he is working as senior principal scientist at CSIR- Institute of Himalayan Bioresource Technology, India. He is a member of several editorial boards of international journals, national and international societies and reviewer of several international repute journals. His interest in chemical, toxicological and pharmacological research resulted in several high impact publications, patents and books.

Research Interest: Natural Product Chemistry, Toxicology, Spectroscopy, Essential Oils

List of Publications:

1. Vijai K. Agnihotri, Rajendra K. Thappa, Baleshwar Meena, Bal K. Kapahi, Rajendra K. Saxena, Ghulam N. Qazi, Shri G. Agarwal. Essential Oil Composition of Aerial Parts of Angelica glauca  Edgew growing wild in North-West Himalaya (India). Phytochemistry, 2004, 65, 2411-2413 (doi:10.1016/j.phytochem.2004.07.004).
   
2. Agnihotri, V. K.; Agarwal, S. G.; Dhar, P. L.; Thappa, R. K.; Baleshwar; Kapahi, B. K.; Saxena, R. K.; Qazi, G. N.  Essential oil composition of Mentha pulegium L. growing wild in the north-western Himalayas India.  Flavour and Fragrance Journal, 2005, 20(6), 607-610 (doi: 10.1002/ffj.1497).
3. Vijai K. Agnihotri, Surrinder K. Lattoo, Rajendra K. Thappa, Pinki Kaul, Ghulam N. Qazi, Autar K. Dhar, Amit Saraf, Bal K. Kapahi, Rajendra K. Saxena, Shri G. Agarwal. Chemical Variability in the Essential Oil Components of Achillea millefolium Linn. From Different Himalayan Habitats (India). Planta Medica, 2005, 71, 280-283 (doi: 10.1055/s-2005-837828).
4. Vijai K. Agnihotri, Hala N. ElSohly, Shabana I. Khan, Melissa R. Jacob, Vaishali C. Joshi, Troy Smillie, Ikhlas A. Khan, Larry A. Walker. Constituents of Nelumbo nucifera leaves and their Antimalarial and Antifungal  activity. “Phytochemistry Letters” 2008, 1, 89-93 (doi:10.1016/j.phytol.2008.03.003).
5. Vijai K. Agnihotri, Hala N. ElSohly, Troy J. Smillie, Ikhlas A. Khan, Larry A. Walker. New Labdane Diterpenes from Leonurus cardiaca. “Planta Medica” 2008, 74, 1288-1290  (doi: 10.1055/s-2008-1081304).
6. Vijai K. Agnihotri, Hala N. ElSohly, Shabana I. Khan, Troy Smillie, Ikhlas A. Khan, Larry A. Walker. Antioxidant Constituents of Nymphaea caerulea Flowers. “Phytochemistry” 2008, 69, 2061-2066 (doi:10.1016/j.phytochem.2008.04.009).
7. Vijai K. Agnihotri, Hala N. ElSohly, Troy J. Smillie, Ikhlas A. Khan, Larry A. Walker. Constituents of Leonotis leonurus Flowering Tops. “Phytochemistry Letters” 2009, 2, 103-105 (doi:10.1016/j.phytol.2009.02.001).
8. Sarang Bani, Anjali Pandey, Vijai K Agnihotri, Vijaylata Pathania, Bikram Singh. Selective Th2 up-regulation  by Crocus sativus, a neutraceutical spice. “Evidence-Based Complementary and Alternative Medicine” 2011, 2011: 639862, 9 pages (doi:10.1155/2011/639862).
9. Mayanka Walia, Tavleen S Mann, Dharmesh Kumar, Vijai K Agnihotri*, Bikram Singh. Chemical Composition and In-Vitro Cytotoxic Activity of Essential Oil of Leaves of Malus domestica Growing in Western Himalaya (India). “Evidence-Based Complementary and Alternative Medicine”, 2012, 2012: 649727, 6 pages (doi:10.1155/2012/649727).
10. Vijai K Agnihotri*. Recent trends in essential oil sciences. “Indian Perfumer”, 2012, 56(4), 31-38.
11. Wajaht A. Shah, Mohd Yousuf Dar, M. Iqbal Zagar, Vijai K. Agnihotri, M.A. Qurishi & Bikram Singh. Chemical composition and antimicrobial activity of the leaf essential oil of Skimmia laureola growing wild in Jammu and Kashmir, India. “Natural Product Research”, 2013, 27(11), 1023-1027 (doi: 10.1080/14786419.2012.696252).
12. Rakesh Kumar, Saurabh Sharma, Swati Sood, Vijai K Agnihotri, Bikram Singh. Effect of diurnal variability and storage conditions on essential oil content and quality of damask rose (Rosa damascena Mill.) flowers in north western Himalayas. “Scientia Horticulturae”, 2013, 154, 102-108 (doi: 10.1016/j.scienta.2013.02.002).
13. Rakesh Kumar, Saurabh Sharma, Swati Sood, Vijai K. Agnihotri. Agronomic interventions for improvement of essential oil content and composition of damask rose (Rosa damascena Mill.) under western Himalayas.
14. “Industrial Crops and Products”, 2013, 48, 171-177 (doi: 10.1016/j.indcrop.2013.04.020).
15. Vijai K Agnihotri*, Soni Thakur, Arvind Sharma, Swaty Sood, Rakesh Kumar, Probir K Pal, Arvind Gulati, Bikram Singh. Essential oil composition and antimicrobial activity of  leaves and stem of Stevia rebaudiana Bertoni cultivated in the Western Himalaya, India. “Indian Perfumer”, 2013, 57(2), 25-30.
16. Kamal Kant, Mayanka Walia, Vijai K Agnihotri*, Vijaylata Pathania, Bikram Singh. Evaluation of antioxidant activity of Picrorhiza kurroa (leaves) extracts. “Indian Journal of Pharmaceutical Sciences”, 2013, 75(3), 324-329 (doi:10.4103/0250-474X.117438).
17. Probir K Pal, Vijai K Agnihotri, Gopichand, Rakesh D Singh. Impact of level and timing of pruning on flower yield and secondary metabolites profile of Rosa damascena under western Himalayan region. “Industrial Crops and Products”, 2014, 52, 219-227 (doi: 10.1016/j.indcrop.2013.10.022).
18. Mayanka Walia, Upendra Sharma, Vijai K Agnihotri*, Bikram Singh*. Silica-Supported Boric Acid Assisted Conversion of Mono- and Poly-saccharides to 5-Hydroxymethylfurfural in Ionic Liquid. “RSC Advances”, 2014, 4 (28), 14414 – 14418 (doi:10.1039/C4RA01771D).
19. Rakesh Kumar, Saurabh Sharma, Swati Sood, Vijai K. Agnihotri, Virendra Singh and Bikram Singh. Evaluation of several Rosa damascena varieties and Rosa bourboniana accession for essential oil content and composition in western Himalayas. “Journal of Essential Oil Research”, 2014, 26(3), 147-152 (doi:10.1080/10412905.2013.829004).
20. Tavleen S. Mann, Vijai K. Agnihotri*, Dharmesh Kumar, Probir K. Pal, Rajkesh Koundal, Ashish Kumar, Yogendra S. Padwal. In-Vitro Cytotoxic Activity Guided Essential Oil Composition of Flowering Twigs of Stevia rebaudiana. “Natural Product Communications”, 2014, 9 (5), 715-718.
21. Vijai K Agnihotri*. Anabaena flos-aquae. “Critical Reviews in Environmental Science and Technology”, 2014, 44 (18), 1995-2037 (ISSN: 1064-3389 print / 1547-6537 online; doi:10.1080/10643389.2013.803797).
22. Ashish Kumar, Shiv Kumar, Dharmesh Kumar, Vijai K Agnihotri*. UPLC/MS/MS method for quantification and cytotoxic activity of sesquiterpene lactones isolated from Saussurea lappa. “Journal of Ethnopharmacology”, 2014, 155(2), 1393-1397 (doi: 10.1016/j.jep.2014.07.037).
23. Vijai K Agnihotri*, Soni Thakur, Vijaylata Pathania, Gopi Chand. A New Dihomosesquiterpene, Termioic acid A, from Curcuma aromatica. “Khimiya Prirodnykh Soedinenii” No. 4, 2014; 577-579 “Chemistry of Natural Compounds”, 2014, 50(4), 665-668 (doi: 10.1007/s10600-014-1048-z).
24. Vijai K Agnihotri*. Crocus sativus Linn.: An Informative Review. “Aperito Journal of Advanced Plant Biology”, 2015, 1:1, 29 pages (doi:10.14437/AJAPB-1-103).
25. Rajkesh Koundal, Kiran Rawat, Vijai K. Agnihotri*, Ramjeelal Meena, Gopichand, Rakesh D. Singh, Yogendra S. Padwad. Temporal and spatial variation in quality of essential oil of Hedychium spicatum and evaluation of its antioxidant activity. “Journal of Essential Oil Research”, 2015, 27(3), 217-224 (doi:10.1080/10412905.2015.1006738).
26. Rajkesh Koundal, Ashish Kumar, Soni Thakur, Vijai K Agnihotri*, Gopi Chand, Rakesh D. Singh. Seasonal variation in phytochemicals of essential oil from Juniperus communis needles in western Himalaya. “Journal of Essential Oil Research”, 2015, 27(5), 406-411 (doi:10.1080/10412905.2015.1043399).
27. Mayanka Walia, Shiv Kumar, Vijai K. Agnihotri*. UPLC-PDA quantification of chemical constituents of two different varieties (golden and royal) of apple leaves and their antioxidant activity. “Journal of the Science of Food and Agriculture”, 2015, Published Online (doi:10.1002/jsfa.7239).
28. Antim K. Maurya, Renuka Devi, Ashish Kumar, Rajkesh Koundal, Soni Thakur, Anamika Sharma, Dharmesh Kumar, Rakshak Kumar, Yogendra S. Padwad, Gopi Chand, Bikram Singh, and Vijai K. Agnihotri*. Chemical composition, cytotoxic and antibacterial activities of essential oils of cultivated clones of Juniperus communis and wild Juniperus Species. “Chemistry & Biodiversity”, 2018, 15, e1800183(1-13) (DOI: 10.1002/cbdv.201800183).
29. Ashish Kumar, Dharmesh Kumar, Antim K Maurya, Yogendra S Padwad, Vijai K Agnihotri*. Synthesis of new heterocyclic amino derivatives of alantolactone and their cytotoxic activity. “Journal of Heterocyclic Chemistry”, 2018, 55, 2715-2721 (DOI: 10.1002/jhet.3328).
30. Soni Thakur, Rajkesh Koundal, Dharmesh Kumar, Antim K Maurya, Yogendra S. Padwal, Brij Lal, Vijai K Agnihotri^*. Volatile Composition and Cytotoxic Activity of Aerial Parts of Crassocephalum crepidioides growing in Western Himalaya, India. “Indian Journal of Pharmaceutical Sciences”, 2019, 1, 167-172.
31. Ashish Kumar, Vijai K. Agnihotri*. Phytochemical studies of Jurinea macrocephala roots from western Himalaya. “Natural Product Research”, 2020, 34(3), 421-424 (DOI:10.1080/14786419.2018.1530233).
32. Rajkesh Koundal, Shudh Kirti Dolma, S.G. Eswara Reddy, Anuja, Gopichand and Vijai K. Agnihotri*. Chemical composition and insecticidal properties of essential oils against diamondback moth (Plutella xylostella L.). “Toxin Reviews”, 2020, 39(4), 371-381 (DOI: 10.1080/15569543.2018.1536668).
33. Mahpara Qadir, Antim K. Maurya, Ajaz A. Waza, Vijai K. Agnihotri, Wajaht A. Shah. Chemical composition, antioxidant and cytotoxic activity of Artemisia gmelinii essential oil growing wild in Kashmir valley. “Natural Product Research”, 2020, 34(22), 3289-3294 (DOI: 10.1080/14786419.2018.1557178).
34. Ashish Kumar, Shiv Kumar, Antim K. Maurya, Vijai K. Agnihotri*. NMR based metabolic profiling of  Saussurea lappa roots and aerial parts from Western Himalaya. “Analytical Chemistry Letters”, 2020, 10(4), 428-441 (DOI: 10.1080/22297928.2020.1796783).
35. Mahpara Qadir, Antim K. Maurya, Vijai K. Agnihotri, Wajaht A. Shah. Volatile Composition, Antibacterial and Antioxidant Activities of Artemisia tournefortiana Reichb. from Kashmir, India. “Natural Product Research”, 2021, 35(1), 152-156 (DOI: 10.1080/14786419.2019.1613990).
36. Antim K. Maurya, Anamika Sharma, Kushal Kumar, Ram Chander, Ashish Kumar, Dharmesh Kumar, Yogendra S. Padwad, Gopi Chand, Vijai K. Agnihotri^*. Comparative studies of essential oils composition and cytotoxic activity of Valeriana jatamansi Jones. “Journal of Essential Oil Research”, 2021, 33(6), 584-591 (DOI: 10.1080/10412905.2021.1966846).
37. Sachin Vashisath, Antim K. Maurya, Vijai K. Agnihotri^*. Comparative chemical profiling of Zanthoxylum armatum DC. from western Himalayan bioresource. “Journal of Essential Oil Research”, 2021, 33(6), 592-600 (DOI:10.1080/10412905.2021.1975579).
38. Ashish Kumar, Vijai K. Agnihotri*. NMR based profiling of sesquiterpene lactones in Saussurea lappa roots collected from different location of Western Himalaya. “Natural Product Research”, 2022, 36(2), 621-624 (DOI: 10.1080/14786419.2020.1789635).
39. Mahpara Qadir, Antim K. Maurya, Vijai K. Agnihotri, Wajaht A. Shah. Selective and efficient synthesis of 1,5-benzodiazepin-2-one and amino chromenes as biologically versatile scaffolds. “Analytical Chemistry Letters”, 2022, 12(1), 77-85 (DOI:10.1080/22297928.2021.2019612).
40. Antim K Maurya, Anamika Sharma, Srijana Mukhia, Deeksha Rani, Ashish Kumar, Dharmesh Kumar, Rakshak Kumar, Yogendra S Padwad, Gopi Chand, Vijai K. Agnihotri*. Essential Oil Composition, in vitro Biological Activities and Safety Evaluation of Cultivated Hedychium spicatum Seeds. “Indian Journal of Pharmaceutical Sciences”, 2022, 84(3) 783-790 (DOI: 10.36468/pharmaceutical-sciences.973).
41. Antim K. Maurya, Ashish Kumar, Vijai K. Agnihotri^*. New iridoids from the roots of Valeriana jatamansi Jones. “Natural Product Research”, 2022, 36(13), 3360-3367 (DOI:10.1080/14786419.2020.1858412).
42. Antim Kumar Maurya, Neha Baliyan, Rakshak Kumar, Vijai Kant Agnihotri*. Synthesis of Sulfur-Containing Analogues of Hedychenone, a Labdane Diterpenoid from Hedychium spicatum. “Journal of Natural Products”, 2022, 85, 1691-1696 (DOI: 10.1021/acs.jnatprod.2c00112).
43. Mahpara Qadir, Nisar A. Dangroo, Vijai K. Agnihotri, Wajaht A. Shah.  Isolation, characterisation, antifungal activity and validated UPLC/MS/MS method for quantification of novel compound from Artemisia tournefortiana Reichb. “Natural Product Research”, 2022, 36(19), 4990-5000 (DOI:10.1080/14786419.2021.1915310).
44. Vinesh Sharma, Birbal Singh, VK Agnihotri, Rinku Sharma1, Devi Gopinath, Gauri Jairath, Jyoti Babu Dhar and Gorakh Mal. Fatty Acids Profile of Himacahli Pahari Cattle and Gaddi Goat Milk. “Acta Scientific Veterinary Sciences”, 2022, 4, 103-109 (DOI:10.31080/ASVS.2022.04.0521).
45. Antim K. Maurya, Sachin Vashisath, Gaurav Aggarwal, Vikas Yadav, Vijai K. Agnihotri*. Chemical Diversity in Needles Essential Oils of Four Pinus Species from Northwestern Himalaya, India. “Chemistry & Biodiversity”, 2022, 19, e202200428 (1-9 pages) (DOI: 10.1002/cbdv.202200428).
46. Antim K. Maurya, Kanika Devi, Vijai K. Agnihotri*. Chemical profiling and α-glucosidase inhibitory activity of essential oils extracted with two methods from some North western Himalayan aromatic crops. “Natural Product Research”, 2023, 37(4), 638-641 (DOI: 10.1080/14786419.2022.2069108).
47. Ram Chander, Antim K. Maurya, Kushal Kumar, Sareeka Kumari, Rakshak Kumar, and Vijai K. Agnihotri*. In vitro antidiabetic and antimicrobial activity of Dracocephalum heterophyllum Benth. essential oil from different sites of North-western Himalayas India. “Natural Product Research”, 2023, 37(6), 1002-1005 (DOI: 10.1080/14786419.2022.2096603).
48. Antim K. Maurya, Gaurav Aggarwal, Sachin Vashisath, Vikas Kumar, Vijai K. Agnihotri*. Chemodiversity and α-glucosidase activity of Eucalyptus species from North-western Himalaya, India. “Chemistry & Biodiversity”, 2023, 20, e202300223(1 of 6) (DOI: 10.1002/cbdv.202300223).
49. Antim K. Maurya, Pawan Kumar, Vijai K. Agnihotri^*. Isocratic elution based analytical method for quantification of phytoconstituents in Hedychium spicatum and evaluation of their α-glucosidase inhibitory activity. “Natural Product Research”, 2024, 38(8), 1430-1434 (DOI: 10.1080/14786419.2022.2140804).
50. Antim K. Maurya, Vijai K. Agnihotri*. Valeriana jatamansi: Bioactive compounds and their medicinal uses. “Current Topics in Medicinal Chemistry”, 2024, 24(9), 757-796 (DOI: 10.2174/0115680266273617240129042653)
51. Ritesh Sharma, Sanjeev K. Sharma, Ram Chander, Rakshak Kumar, Vijai K. Agnihotri*. In-vitro antidiabetic and antimicrobial studies of volatile organic compounds (VOCs) from the roots of Rosa damascena Mill. of North-western Himalaya. “South African Journal of Botany”, 2024, 168(1), 518-528 (DOI: 10.1016/j.sajb.2024.03.051).
52. Antim K. Maurya, Vijai K. Agnihotri*. A new iridoid from the roots of Valeriana jatamansi Jones with α-glucosidase activity. “Natural Product Research”, 2024, 38(14), 2505-2510 (DOI:10.1080/14786419.2023.2187796).
53.  

Research Interest: Theory and Mechanisms of Carcinogenesis and Metastasis; Breast Cancer; Endocrinology

Research Interest: Toxicology And Pharmaceutical Applications Of Decavanadate; Ii) Muscle Contraction And Regulation; Iii) Insulin Mimetic Compounds.

Research Interest: Drug Discovery and Development from Plant Sources. Isolation and Characterization of Bioactive Molecules from High Altitude Medicinal and Aromatic Plants Using Different Separation Techniques Like TLC, Column Chromatography, Preparative TLC, HPLC, HPTLC, LC-MS, GC-FID And GC-MS. Characterization of the Isolated Molecules from the Plants Using Different Spectroscopic Techniques Like 1H NMR, 13C NMR, 2D Techniques, Mass Spectrometry, IR, X-Ray, UV- Visible Etc. Structural Modifications of these Molecules to Value Add their Biological Properties. Chemical Characterization Using Capillary GC-FID and GC-MS Analytical Techniques and Bioevaluation of Essential Oils, Oleoresins and Other Aroma Mixtures Isolated from Aromatic Plants with Main Thrust on Unexplored Flora of the Kashmir Valley

Research Interest: WT1-Specific Cytotoxic T-Lymphocytes That Have The Potential To Attack Tumor Cells

Research Interest: Head And Neck Cancer, Genetics, Molecular Biology, Cell Line, Chemoterapeutics, Genetic Polymorphisms

Research Interest: Discovery of Novel Antiviral, Anticancer and Neurodegenerative Diseases-Related Agents Based on The Rational Drug Design Approaches.

Research Interest:Oncology, Radiotherapy, Radiobiology, Head And Neck Cancer; Anti-Cancer Drug Research

Research Interest: Cancer treatment regimens, photodynamic therapy, nanotechnology-enabled drug delivery.

Research Interest: To study the metabolic adaptation for survival occurring in the cancer cells