Research Interest: Gene expression, gene therapy, cell biology, neurodegenerative disease, male and female infertility.

Research Interest: Epidemiology and  pathophysiology of ischemic stroke Inflammatory  activation of the acute phase of acute ischemic stroke in relation of  subtypes of ischemic stroke,CD4+CD28- T cells in acute ischemic stroke  killer cell immunoglobulin-like receptors (KIR) receptors in acute clinical subtypes of acute ischemic stroke Treatment with  high-dose furosemide and small-volume hypertonic saline therapy in refractory heart failure Treatment with  high-dose furosemide and small-volume hypertonic saline therapy in refractory ascites diabetic foot as a cardiovascular risk marker Anderson-Fabry disease

Research Interest: Water composition and nutrition Genetics in Inborn Error Metabolism Nutrition in Pediatrics

Current position:
2011- present : Associate Professor of Medical Genetics (Area A1/06- SSD MED03), University of Chieti-Pescara  Italy On April  2017, VG obtained the National Scientific Qualification as Full Professor  in Medical Genetics  (SSD MED/03)

Previous positions:
2005-2011:  University Researcher (Medical Genetics - MED 03) University of Chieti-Pescara ( Italy)
2002-2005: Post-Phd Fellowship supported by University of Chieti.
1995- Fellowship supported by European Structural Funds. Research area:  Biological and Medical Science carried out at the  Centro di Genetica Evoluzionistica- CNR Rome

Research Interest: During the course of her scientific activity, VG  worked in the field of molecular genetics, using the most recent techniques for the study of gene mutations causing pathologies such as male infertility, short stature (linked to mutations of the SHOX gene), familiar breast cancer (due to mutations of the BRCA1 and BRCA2 genes), Van Der Woude syndrome (IRF6 gene), and several neuromuscular diseases (Duchenne Muscular Dystrohpy, distal SMA, and others).
 She is head of a research team, working in the CAST research Centre of Chieti University specialized in molecular genetics.
 During these years VG primary interest was the study of the molecular basis of human reproduction and  she is currently investigating molecular mechanisms involved in oocyte competence and male infertility.
 These studies have been carried out by VG using a variety of molecular genetics technique like PCR, Southern Blot, DNA sequencing, as well as Multiple Ligation-Dependent Probe Amplification (MLPA). In the last few years, she has employed Real Time PCR, microarray , HRM, pyrosequencing and NGS technologies to investigate the modulation of gene expression profile in  different  models and SNPs (oocyte mitochondrial DNA, sperm, cumulus cells, oocyte, Transgenic Mouse Models of AD, stem cells).

URL: https://www.unich.it/ugov/person/1475

Number of publications: 10

Research Interest: Oncology, Genetics and Gene Therapy, Signaling Pathways, Molecular Research, Cell Biology, Signal transduction.

Research Interest: Mechanism(s) of neurotransmitter and hormone synthesis, secretion and action, and the associated cellular regulatory pathways and their modulation by pharmacological agents. I am also interested in the effects of pharmacological and dietary modulation (medical foods, herbs, behavioural techniques etc) of metabolic, cellular, organ and systemic levels. I am especially interested in the age-related diseases, such as cancer, neurodegeneration. Expertise in the prevention of CNS/PNS damage in conditions related to metabolic syndrome (diabetes), stroke, ischemia, hypoxia and diseases like Alzheimer’s and Parkinson’s

Research Interest: My Research Focuses on the Bacterial Pathogens Analysis. It includes: Pathogen Identification (Including MALDI-TOF MS/MS Analysis); Bacteria GWAS Analysis; Infectious Disease Diagnosis; Vaccine Development

Research Interest: Biomarkers for the early detection and targeted therapeutics for triple negative breast cancer, oxidative stress and its role in linking cancer and diabetes, development of protein based biologics, clathrin coated pit-mediated endocytosis and its downstream signaling, drug delivery, syngeneic and xenografts mice model.

Research Interest: Pathology including molecular findings in lung and breast cancer.

Research Interest: Epigenetics, DNA methylation, Gene expression.

Research Interest: Mechanisms of cell signaling pathway of cell death Cancer Biology Mechanisms of anti-cancer effect of cancer chemopreventive agents

Research Interest: Molecular markers Genome, Evolutionary and Population, Genetics, Microbial Genetics

Research Interest: Head and Neck Cancer Objetivos:Epidemiology and Head and Neck pathology. Biomarkers of prognostic in Head and Neck tumors

Research Interest: Processos carcinogênicos e progressão de lesão. Invasão e metastáse. Processos patológicos envolvendo Papilomavirus humano (HPV) Estudos envolvendo análises citológicas e histopatológicos.

Research Interest: Genomics Application in Auditory Disease; Novel Deafness Gene and Mutations Identification; Next Generation Sequencing