Research Interest:  Radiation Oncology, Radiosensitizers, Radiosurgery, Proton Therapy, IMRT, IGRT, CNS Tumors, Thoracic Oncology, Combined Modality Therapy, Clinical Trials

Research Interest: Intensity Modulated Radiation Therapy (IMRT), Image Guided Radiation Therapy (IGRT), Stereotactic Body Radiotherapy (SBRT), Multi-Modality (including Computed Tomography, Magnetic Resonance Imaging, and Magnetic Resonance Spectroscopy) Therapy Targeting and Therapy assessment, and PTV Construction and Tx Delivery in the Presence of Target Motion, 4DCT, 4DCBCT

Research Interest: Oncology, Radiology, Radiation Protection, Radiobiology

1)Cystic  Nephroma: report of a case an review of the literature. A.Baldi, V. De Crescenzo, D. Ranieri Giordano, R. Lamberti, A. Perna, C. Picone, A. Lucariello et al.IN VIVO( IF 1.264) 21.895-896( 2007)

3) ” And what about Gaba Magnetic Resonance Spectroscopy as an Indirect Tool to Evaluate Riluzole Efficacy in Amyotrophic Lateral Sclerosis? Raffaella Mormile1 *, Gennaro Mazzei2 , Anna Russo2 , Carmine Picone2 , Mario De Michele3 and Bruno Guida4  J Mol Biomark Diagn 2013, 4:3 IF 3,370

5)Cetuximab, irinotecan and  fluorouracile in first-line treatment-selected advanced colorectal cancer patient : the CIFRA study protocol Ottaiano A., Scala S, Normanno N, Delrio P., Picone C., Nasti G.BMC Cancer 19(1) 899.(IF 3.288)

7)The safety of atezolizumab plus chemotherapy for the treatment of metastatic lung cancer Manzo, A., Carillio, G., Montanino, A.,Picone C. ...Normanno, N., Morabito, A. Expert Opinion on Drug Safety, 2020, 19(7), pp. 775–783

9)Aflibercept or bevacizumab in combination with FOLFIRI as second-line treatment of mRAS metastatic colorectal cancer patients: the ARBITRATION study protocol Ottaiano, A., Scala, S.,Picone C. Santorsola, M., ...Caraglia, M., Nasti, G. Therapeutic Advances in Medical Oncology, 2021, 13

11) Surgery in small-cell lung cancer Martucci, N., Morabito, A., La Rocca, A. , Picone C., ...Normanno, N., La Manna, C. Cancers, 2021, 13(3), pp. 1–14, 39

13) Radiomics in hepatic metastasis by colorectal cancer Granata V.a,Fusco R.a, Barretta M.L.a,Picone C.a,Avallone A.b, et  Belli A.c,Patrone R.c,Ferrante M.d,Cozzi D.e, Grassi R.d,Grassi R.d, f,Izzo F.c  Infectious Agents and Cancer ( 2021) Volume 16, Issue 1

15) RET inhibitors in non-small-cell lung cancer Cascetta, P., Sforza, V., Manzo, A.,C.Picone .Normanno, N., Morabito, A. Cancer  s 2021, 13(17), 4415

17) Evolution of ct findings and lung residue in patients with covid-19 pneumonia: Quantitative analysis of the disease with a computer automatic tool Grassi, R., Cappabianca, S., Urraro, F., C.Picone...Grassi, R., Miele, V. Journal of Personalized Medicine, 2021, 11(7), 641

19)  RET inhibitors in non-small-cell lung cancer Cascetta, P., Sforza, V., Manzo, A., ...Normanno, N., Morabito, A. Cancers, 2021, 13(17), 441

21) Liquid BiopsyTesting for the Management of Patient with Non-Small Cell Lung Cancer Carrying a Rare Exon-20 EGFR Insertion Morabito, A., Manzo, A., Montanino, A., ...Lastoria, S., Normanno, N. Oncologist 2022, 27(1), pp. 7–12

23) Imaging Assessment of Interval Metastasis from Melanoma Simonetti, I., Trovato, P., Granata, V., ...Sandomenico, F., Petrillo, A. Journal of Personalized Medicine, 2022, 12(7), 1033

25) Lurbinectedin in small cell lung cancer Manzo, A., Sforza, V., Carillio, G., ...Normanno, N., Morabito, A.

Frontiers in Oncology, 2022, 12, 932105

27) Risk Management Activities in a Lung Cancer Multidisciplinary Team at a Comprehensive Cancer Center: Results of a Prospective Analysis. Morabito A, Mercadante E, Muto P, Palumbo G, Manzo A, Montanino A, Sandomenico C, Sforza V, Costanzo R, Damiano S, La Manna C, Martucci N, La Rocca A, De Luca G, Totaro G, De Cecio R, Picone C, Piccirillo MC, De Feo G, Tracey M, D'Auria S, Normanno N, Capasso A, Pascarella G. JCO Oncol Pract. 2022 Nov 16:OP2200358. doi: 10.1200/OP.22.00358. Online ahead of print.PMID: 36383923

29) Radiation Recall Pneumonitis: The Open Challenge in Differential Diagnosis of Pneumonia Induced by Oncological Treatments. Grassi F, Granata V, Fusco R, De Muzio F, Cutolo C, Gabelloni M, Borgheresi A, Danti G, Picone C, Giovagnoni A, Miele V, Gandolfo N, Barile A, Nardone V, Grassi R.J Clin Med. 2023 Feb 10;12(4):1442. doi: 10.3390/jcm12041442

Picone C, Fusco R, Tonerini M, Fanni SC, Neri E, Brunese MC, Grassi R, Danti G, Petrillo A, Scaglione M, Gandolfo N, Giovagnoni A, Barile A, Miele V, Granata C, Granata V.J Clin Med. 2023 Feb 25;12(5):1847. doi: 10.3390/jcm12051847

Research Interest: Head and Neck Cancer, Prediction Models for Radiation-Induced Side Effects, Proton Therapy, Epidemiology

Research Interest: Radiobiology, Target Therapies, Breast Cancer, Prostate Cancer, Biological Target Volume

Research Interest:  Cancer Treatments Utilizing Radiation Therapy with Novel Chemotherapy Agents for Cancers of the Head and Neck Region, Human Papilloma Virus Related Cancers of the Head and Neck, and Novel Chemoradiation Treatment Combinations

Research Interest: Uro-Oncology and Gynae-Oncology

Research Interest: Ultrasound; Elastography; Contrast Enhanced Ultrasound; Renal Biopsy; Renal Focal Lesions; Medical Devices

Research Interest: Head and Neck Imaging (DSCT, CBCT, Fluoroscopy, X-ray), Imaging Applications Related to Radiotherapy, Radiation Protection and Safety, Dosimetry

Research Interest: MRI Physics; System Biology; Physics of Biomedical Microscopy; Ionizing Radiation; Mathematical Modelling of Psyological Systems; Ultrasound; Radiation Therapy; Safety in Medical Devices;  Simulation Methods in Medical Engineering

Research Interest: Neuroradiology, Pediatric Radiology, Oncology

Research Interest: Image Guided Radiation Therapy and Accelerated Partial Breast Irradiation

Research Interest: Early Detection of Pneumonitis and Pulmonary Fibrosis in Victims of Radiation Accidents/Patients Receiving High Dose Thoracic Exposure; Chronic Kidney Disease and Lung Toxicity in Patients Who Receive Total Body Irradiation as Part of Preparative Regimen for Bone Marrow Transplantation

Research Interest: Brain Tumor, Pediatric Tumors, Radiation Oncology

Research Interest: Stereotactic Radiosurgery, Palliative Radiation Oncology, Brain Metastasis, Glioblastoma, and Image-Guided Hypofractionated Radiotherapy

Research Interest:  Telomeres, Telomerase, Brain Tumors, Radiation, Sensitivity, Resistance, DNA Damage

Research Interest:  Ultrasound, Obstetrics and Elastography.

Research Interest:  Translational Research, Molecular Imaging in Cancer Therapy, Functional Image-Guided Radiation Therapy, Stereotactic Body Radiation Therapy, Multi-Modality Cancer Therapy Combining Targeted Therapy and Radiation Therapy, Anti-Angiogenic Therapies

Research Interest:  Focused on Fast Abdominal MR Imaging, Cardiac MRI, and Breast MRI and MR Spectroscopy

Research Interest: Image Guided Radiation Therapy (IGRT) and Adaptive Radiation Therapy (ART); Respiration and Motion Management; Clinical Outcome Assessment and Mathematical Modeling

Research Interest: Radiotherapy of Lung Cancer and Primary Liver Carcinoma, Include both Clinical Investigations and Translational Research

Research Interest: Nuclear Medicine, Positron Emission Tomography, Bone Mineral Density Measurement, Clinical Epidemiology

Research Interest: Musculoskeletal Imaging and Nuclear Medicine

Research Interest: Interventional Procedures; Vascular;  Transcatheter Arterial Embolization (TACE); Percutaneous Intraluminal Angioplasty (PTA); Transcatheter Arterial Infusion (TAI); Percutaneous Intravascular Pot-Catheter System Implantation;  Stent Placement (IVC, Renal Artery, Iliac Artery, Etc.); Transcatheter Fibrinolysis. Non-Vascular; Radiofrequency Ablation; Microwave Ablation; Percutaneous Lumbar Diskectomy; Vertebroplasty; Percutaneous Injection of Intradiscal Space with O2/O3 Gas; Percutaneous Abscess/Cyst Drainage;  Percutaneous Nephrostomy; Stent Placement (Biliary And Esophagus);  Percutaneous Biopsy;  Percutaneous Peritoneovenous Shunting; Percutaneous Gastrostomy. Other Cellular and Molecular Biological Techniques: Preparation of Polyclonal Antibody, PCR and RT-PCR, Immunohistochemistry, Confocal Microscopy, Transmission and Scanning Electron Microscopy, Flow Cytometery, Protein Binding in Vitro, TUNEL

Research Interest: Radiation Biology; Radiation Prevention; Using 3DCRT, IMRT, IGRT and SBRT in Clinical Practice; Translational Medicine, Target Delineation Research

Research Interest: SRS, SBRT, Multidiciplenary Cancer Management, Non Invasive Local Therapy, Organ Preservation, Quality of Life, Cancer Care, Concurrent Treatment, Neoadjuvant Treatment

Research Interest: Radiation Therapy, Especially High Precision Radiotherapy (IMRT, IGRT, ART)

Research Interest: Cone-Beam Computed Tomography, Root Canals, Morphology, HIV, Menopause, Radiography, Panoramic, Bone Resorption

Research Interest: Optimization Algorithms; Bone; Osteoporosis; Bone Mineral Density; Bone Mineralization; Hip; Musculoskeletal Imaging

Research Interest: Oncology: Brachytherapy, Head And Neck Cancer, IMRT, Cancer Cervix, Brain Tumours

I hold BSc and MPhil degrees in Biochemistyry from the University of Ghana. I successfully graduated with a PhD in Aging studies (radiation biology) in 2013 with a “Suma cum Laude” from the University of Murcia Spain. This was followed by a one-year post-doctoral fellowship at the Division of Radiobiology, Stellenbosch University where I studied “protein biomarkers for radiation dosimetry”.    

 I was engaged by the Ghana Education Service to teach Chemistry to high school students after my undergraduate studies in 1990, and resigned as a senior Superintendent.

I was employed by the Ghana Atomic Energy Commission in January 1998 as a Research Scientist researching in the use of molecular and isotopic techniques for the diagnosis of  tuberculosis and have since risen to the rank of Chief Research Scientist.

 I was made the Centre Manager of the Applied Radiation Biology Centre of the Radiological and Medical Sciences Research Institute (RAMSRI) here at the GAEC in 2009 until July 2016 where  I became the substantive Deputy-Director of RAMSRI.
 Within the GAEC, I initiated and led some important projects including; International Atomic Energy Agency (IAEA) Coordinated Research Project “Strengthening of “Biological dosimetry” in IAEA Member States and co-investigator of an IAEA marine project RAF 7/0/14,  “The Application of Nuclear Analytical Techniques to Support Harmful Algal Bloom Management In The Context Of Climate And Environmental Change”. Additionally, I was also Chief Scientific Investigator of IAEA CRP: - “Assessment of food chain transfer of harmful algal toxins and heavy metals in some marine organisms in the coastal waters of Ghana”.
 Moreover, I initiated several minor projects since joining the GAEC including pioneering work in the area of botanical medicine hinging around the evaluation of medicinal plant extracts for their radioprotective, radiosensitising and anti-cancer principles. I also pioneered work in the area of biological dosimetry in the GEAC and Ghana.
 I have served on several committees within and outside the the GAEC including the GAEC Corporate Strategic Plan Review Committee, RAMSRI Administrative Committee, RAMSRI Research and Technical Committee. I prrviously served as member of the Presidential Committee on Vaccines Manufacturing in Ghana and currently a member of Governing Board of the National Vaccines Institute (NVI), member of Project steering committee  of Post Covid-19 Skills Development and Productivity Enhancement Project (PSDPEP) and member  and member of the GHS/WHO International Health Regulations (IHR) Steering Committee (Radiation Focal Group).
 Internationally, I previously served as a reviewer for two (2) International Journal and taken part in numerous international conferences and workshops on cancer and radiation biology, biodosimetry, biotechnology and various diverse areas of endeavour. I have also acted as supervisor for undergraduate and postgraduate students but also as an external examiner for PhD theses in Radiobiology, toxicology and radiation protection for some local an international Universities.

 Research Interest: My interest inytersets spans from science education and management, teaching and to life science research in such areas as, Radiobiology, Neutrophils and radiation induced reactive oxygen species. Biodosimetry. Radioprotectors and Radiosensitizers. Cancer biologyand Phytomedicine/natural products.

• Assistant Professor of Cytogenetics, I embarked on my academic journey by pursuing a Bachelor's degree, followed by an MSc and Ph.D. from the Faculty of Science-Ain Shams University. Obtained a Molecular Biology & Genetic Engineering Diploma from VACSERA and the Scientific Informatics Research Academy Center for Biotechnology. Hold a General Diploma in Education from the Institute of Educational Studies and Research at Cairo University. Attended numerous training courses and workshops.
• My expertise in radiation Cytogenetics allows me to investigate the effects of ionizing irradiation on chromosomes both in vivo and in vitro. Deciphering the molecular changes that occur and understanding their potential long-term consequences. Discovering the radioprotective and radiosensitizing effects of various natural and synthesized compounds on normal and tumor cells, with the aim of improving the radiotherapeutic process.
• My research findings have been published in impacted scientific journals, actively collaborated with national institutions, fostering interdisciplinary partnerships. These collaborations have resulted in significant contributions, including a deeper understanding of the cytogenetic effects of radiation & their connection to other biological effects.
• Member of "The Egyptian Society of Nuclear Sciences and Applications" and reviewer for Cell Biology journal U.S.A., and volunteered as a reviewer for 11 journals in ELSEVIER.
  

Research Interest:

• Chromosomal Analysis
• Radiation Cytogenetics
• Comet Assay
• Radioprotectants
• Radiosensitizers
• Antitumors Research
• Tissue Culture